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Alcohol Addiction Drugs in Development by Stages, Target, MoA, RoA,  Molecule Type and Key Players, 2022 Update
Alcohol Addiction Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

Kappa receptor (KOR) function in neurocircuits of addiction. This... |  Download Scientific Diagram
Kappa receptor (KOR) function in neurocircuits of addiction. This... | Download Scientific Diagram

Kappa Opioid Signaling at the Crossroads of Chronic Pain and Opioid  Addiction | SpringerLink
Kappa Opioid Signaling at the Crossroads of Chronic Pain and Opioid Addiction | SpringerLink

Mixed Kappa/Mu Partial Opioid Agonists as Potential Treatments for Cocaine  Dependence - ScienceDirect
Mixed Kappa/Mu Partial Opioid Agonists as Potential Treatments for Cocaine Dependence - ScienceDirect

A Role for Brain Stress Systems in Addiction: Neuron
A Role for Brain Stress Systems in Addiction: Neuron

Selective kappa opioid antagonists for treatment of addiction, are we there  yet? - ScienceDirect
Selective kappa opioid antagonists for treatment of addiction, are we there yet? - ScienceDirect

Agonist vs Antagonist Drugs for Addiction Treatment - Oro House
Agonist vs Antagonist Drugs for Addiction Treatment - Oro House

Kappa opioid receptor signaling in the brain: Circuitry and implications  for treatment - ScienceDirect
Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment - ScienceDirect

Insights from Preclinical Choice Models on Treating Drug Addiction: Trends  in Pharmacological Sciences
Insights from Preclinical Choice Models on Treating Drug Addiction: Trends in Pharmacological Sciences

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist  Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical  Neuroscience
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience

Molecular mechanism of biased signaling at the kappa opioid receptor |  Nature Communications
Molecular mechanism of biased signaling at the kappa opioid receptor | Nature Communications

Pharmaceuticals | Free Full-Text | Biased, Bitopic, Opioid–Adrenergic  Tethered Compounds May Improve Specificity, Lower Dosage and Enhance  Agonist or Antagonist Function with Reduced Risk of Tolerance and Addiction
Pharmaceuticals | Free Full-Text | Biased, Bitopic, Opioid–Adrenergic Tethered Compounds May Improve Specificity, Lower Dosage and Enhance Agonist or Antagonist Function with Reduced Risk of Tolerance and Addiction

Frontiers | A Review of the Therapeutic Potential of Recently Developed G  Protein-Biased Kappa Agonists
Frontiers | A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists

Frontiers | The Kappa Opioid Receptor: From Addiction to Depression, and  Back
Frontiers | The Kappa Opioid Receptor: From Addiction to Depression, and Back

Opioid agonists, mixed agonist-antagonists and partial agonists | Osmosis
Opioid agonists, mixed agonist-antagonists and partial agonists | Osmosis

The blocking of kappa‐opioid receptor reverses the changes in dorsolateral  striatum dopamine dynamics during the amphetamine sensitization - Azocar -  2019 - Journal of Neurochemistry - Wiley Online Library
The blocking of kappa‐opioid receptor reverses the changes in dorsolateral striatum dopamine dynamics during the amphetamine sensitization - Azocar - 2019 - Journal of Neurochemistry - Wiley Online Library

Antagonist for the Kappa Opioid Receptor - Probe Reports from the NIH  Molecular Libraries Program - NCBI Bookshelf
Antagonist for the Kappa Opioid Receptor - Probe Reports from the NIH Molecular Libraries Program - NCBI Bookshelf

Development of a Selective Peptide κ-Opioid Receptor Antagonist by  Late-Stage Functionalization with Cysteine Staples | Journal of Medicinal  Chemistry
Development of a Selective Peptide κ-Opioid Receptor Antagonist by Late-Stage Functionalization with Cysteine Staples | Journal of Medicinal Chemistry

A systematic review on the kappa opioid receptor and its ligands: New  directions for the treatment of pain, anxiety, depression, and drug abuse -  ScienceDirect
A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse - ScienceDirect

Psychoactives | Free Full-Text | The Role of the Dynorphin/Kappa Opioid  Receptor System in the Actions of Alcohol
Psychoactives | Free Full-Text | The Role of the Dynorphin/Kappa Opioid Receptor System in the Actions of Alcohol

Cocaine Use Reduction with Buprenorphine (CURB: CTN-0048): Protocol  Overview. - YouTube
Cocaine Use Reduction with Buprenorphine (CURB: CTN-0048): Protocol Overview. - YouTube

A single, extinction-based treatment with a kappa opioid receptor agonist  elicits a long-term reduction in cocaine relapse | Neuropsychopharmacology
A single, extinction-based treatment with a kappa opioid receptor agonist elicits a long-term reduction in cocaine relapse | Neuropsychopharmacology

Effects of Kappa opioid receptor blockade by LY2444296 HCl, a selective  short-acting antagonist, during chronic extended access cocaine  self-administration and re-exposure in rat | Request PDF
Effects of Kappa opioid receptor blockade by LY2444296 HCl, a selective short-acting antagonist, during chronic extended access cocaine self-administration and re-exposure in rat | Request PDF

Kappa Opiate Receptor Agonist - an overview | ScienceDirect Topics
Kappa Opiate Receptor Agonist - an overview | ScienceDirect Topics

Conformational Constraint between Aromatic Residue Side Chains in the  “Message” Sequence of the Peptide Arodyn Using Ring Closing Metathesis  Results in a Potent and Selective Kappa Opioid Receptor Antagonist |  Journal of
Conformational Constraint between Aromatic Residue Side Chains in the “Message” Sequence of the Peptide Arodyn Using Ring Closing Metathesis Results in a Potent and Selective Kappa Opioid Receptor Antagonist | Journal of